Independent education · Sources and limitations documented
Portfolio / TKA perioperative analgesia

Evidence review

Source snapshot · 5 November 2026

2026.10-rc2 - educational review candidate

Educational work by a pre-medical student — not medical advice. Not a clinical protocol, prescription, or patient handout, and not for patient care. See DISCLAIMER.

Revised 27 October 2026 after the rc1 PRs were merged.

This pass corrects newly identified source and software defects and deliberately narrows unsupported clinical/methodological content. Earlier versions remain recoverable in Git history. See PUBLICATION_REVIEW.md for the precise scope and limitations, PROVENANCE.md for author statements, and RELEASE_MANIFEST.json for current-file hashes.

The candidate is not a clinical protocol, validated controller, systematic/scoping review certification, or legal opinion. No repository visibility change is included.

Applied example set — 28 October 2026

Added 6 topic-specific male/female case pairs, a local copy of the shared anesthesia-options set, two levels of source mapping and an explicit verification standard. The profiles are entirely synthetic; the source checks are scoped and do not certify clinical validity. Existing clinical/manuscript text and PDF exports are preserved.

29 October 2026 — Portfolio presentation and reading path

Added a concise reader’s guide, explicit AI-assistance/authorship scope and review-status notes. Linked the portfolio home and corrected navigation wording. This presentation pass preserves substantive manuscripts, casebooks, code and existing exports. Repository visibility is unchanged.

November 2026 — accuracy and governance review

5 November 2026. Precision fixes from an independent source re-check (no Critical or Major findings):

  • Main map and modality note: Johnson et al. 2016 is described as pooling randomized and prospective comparative studies; ICAROS 2019 additionally included retrospective/database observational studies. The ICAROS knee-arthroplasty neuraxial preference is now stated as a weak recommendation on low-level evidence (hip: strong).
  • Adjunct note: PROSPECT 2022 does not recommend ketamine after TKA (conflicting procedure-specific evidence). The 2022 add-on trial is now cited by author, title and journal (Muñoz-Leyva et al., Anesthesiology 2022;137:459-470). The withdrawn PMID 23364596 is described only as not corresponding to a TKA lidocaine trial.
  • Regional note and main map: the Cochrane adductor canal review (Schnabel 2019) is noted to cover adult knee surgery (18 TKA, 7 arthroscopic trials).
  • Applied cases and EXAMPLE_SOURCE_AUDIT.json: TK-02 now cites Hussain et al. 2021 (iPACK) instead of the LAST checklist; the Beloeil (POFA) scope now states it was a major non-cardiac surgery trial, not TKA, replacing text copied from another repository; duplicate DOI links removed; the Smart NOA walkthrough reference is now an explicit link to the separate repository.
  • Main map: title and README now say "selected-source narrative evidence map" (legacy "Scoping-Review" filenames kept for link continuity); reference list rewritten as full citations with printed DOIs/PMIDs; inline cross-document links rendered as plain filenames so the PDF export does not show raw Markdown; "Foo et al.." typo removed. The PDF export is stale until rebuilt.
Source and scope

Published from tka-perioperative-review/RELEASE_NOTES.md at revision b4a47b53c1b3. Full source text is retained; HTML presentation does not establish independent clinical review. The retained filename says Scoping-Review; the current work is a selected-source narrative map.