Independent education · Sources and limitations documented
Portfolio / HLA approximation in glioma

Research methods

Source snapshot · 5 November 2026

Disclaimer

Applies to every file in this repository, to its releases, and to copies of its content on collinbgeorge.com.

Not medical advice

This repository is independent research by a pre-medical student who is not a licensed clinician. Nothing here is:

  • medical advice
  • a clinical protocol, guideline, order set, or decision aid
  • a diagnostic, prognostic, or treatment-selection tool
  • a patient handout

Nothing here should be used to diagnose, treat, or manage any patient, or to select patients for any therapy. Patients should consult their own licensed clinicians. In an emergency, call 911 or your local emergency number.

Data and results

  • Public, open-access data only. The analysis uses open-access TCGA PanCanAtlas files listed in docs/data_acquisition.md. No controlled-access data and no data use agreement are involved, and raw inputs are not redistributed here.
  • Work in progress. Stages 1 and 2 are complete; Stage 3 (binding prediction) is pending. Stage 3 results are not yet available, and the study's conclusions depend on them.
  • Pre-specified plan. ANALYSIS_PLAN.md was written before any prediction was performed and commits to reporting both outcomes, including a null result.
  • Stated limits. The README lists the study's limitations, including missense-only scope, one disease, one predictor and one cohort, and the comparison caveat if patient-specific HLA genotypes cannot be obtained. No peer review is recorded in this repository.

No affiliation or endorsement

This is independent research, conducted outside the scope of any employment and not issued on behalf of any institution. It is not affiliated with, reviewed by, or endorsed by any university, hospital, health system, employer, professional society, or government agency, including the data providers named above. Mentions of an organization or data source do not imply endorsement.

AI assistance

This disclaimer file was added in November 2026 during an AI-assisted portfolio review. It makes no statement about how the analysis, code, or results were produced.

No warranty; limitation of liability

This material is provided "as is" and "as available," without warranties of any kind, express or implied, including accuracy, completeness, currency, merchantability, fitness for a particular purpose, and non-infringement. To the fullest extent permitted by law, the author is not liable for any loss, injury, or damage arising from use of, or reliance on, this material. Use is at the user's own risk. These terms supplement, and do not narrow, the warranty disclaimer and limitation of liability in the MIT License (see LICENSE) for code and in Sections 5 and 6 of the Creative Commons Attribution 4.0 International legal code for derived data tables.

Corrections

Errors can be reported through GitHub Issues.


© 2026 Collin B. George · Code under the MIT License (see LICENSE); derived data tables under CC BY 4.0 · Third-party data retain their own terms.

Source and scope

Published from hla-approximation-glioma/DISCLAIMER.md at revision 30411472cf19. Full source text is retained; HTML presentation does not establish independent clinical review. Repository reports Stages 1–2 complete and binding prediction pending; not clinical validation.